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Scientist II - Lung Microbiome Research AstraZeneca

Location: Gaithersburg, Maryland, United States
Job reference: R-041874
Posted date: Jan. 02, 2019

MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you'll have the opportunity to make a difference in people's lives every day. As one of the world's premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease. As a Scientist II in our Respiratory, Inflammation, and Autoimmune (RIA) Research team in Gaithersburg, MD, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives.

We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we're industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

We are seeking a highly motivated and skilled Scientist with a strong background in biology of Host & Microbe interaction to join the RIA Research Department in Gaithersburg, MD, and take a role in developing strategy and delivering novel solutions to design microbiome-based interventions for respiratory diseases. Our team collaborates with Microbial Sciences researchers to drive projects targeting lung microbiome and host defense mechanisms in respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD). You will be expected to lead a small team (2 reports), and drive research projects to increase our understanding of the role of lung microbiome and its interaction with host immune system as a regulator of disease development and as a cause of disease exacerbations. You will be expected to identify new targets for drug discovery and development, and contribute to the design and development of portfolio projects in collaboration with Translational Medicine and Clinical Development. Our team works closely with academic partners and you will be expected to create potential external collaborations to enhance our success in drug discovery. Regular presentations and publications of cutting-edge science are expected in this position.

The research will be conducted in Medimmune's state-of-the-art laboratories located in Gaithersburg, Maryland, outside Washington, DC area. The successful candidate will benefit from daily interaction and collaboration with other highly accomplished scientists with diverse areas of expertise with whom they will collaborate. The position offers a unique opportunity for a talented scientist to work in a dynamic and innovative environment and develop their career at the interface of basic research and drug discovery.

Position Requirements:

  • PhD in Life Sciences with 3-7 years of relevant PostDoctoral Research experience; or Master's degree in Life Sciences with 10-13 years of relevant experience; or Bachelor's Degree in the Life Sciences with 13-15 years of relevant experience
  • Extensive knowledge in biology of host and microbe interaction
  • Demonstrated ability to conduct high-level, cutting edge research projects
  • Strong publication record, including 4+ first-author publications in high-impact journals
  • Prior experience in lung biology and mucosal immunology
  • Highly motivated and capable of working independently as well as collaboratively
  • Major techniques experience includes:

Cell co-culture models

Multi-omics methodology

Immunohistochemistry and confocal microscopy

Flow cytometry

  • In vivo expertise
  • Highly organized, with strong data presentation/communication skills

Preferred experience:

  • Industry experience is strongly preferred but not a requirement
  • Image analysis experience is desirable

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.